Improving Vision with Non-invasive Bioelectricity – A New Hope
Dong Feng Chen, MD, PhD
Schepens Eye Research Institute of Mass Eye and Ear, Department of Ophthalmology,
Harvard Medical School
Emerging research has shown that transpalpebral electrical stimulation (ES) of the eye may be a
powerful method for preserving vision in otherwise irreversible blinding diseases such as
choroideremia (CHM) among others. This approach, commonly used to restore muscle and neural
functions, may offer a unique way to interact with the neuroretina for disease management and
preservation of vision. Our recent studies have highlighted the significant benefits of transpalpebral
ES at specific parameters for preserving vision in several mouse models of retinal degeneration.
These effects are believed to help with improved photoreceptor survival and function, and the
inhibition of neuroinflammation. The safety and non-invasive nature of this treatment supports its
potential for future large-scale trials in treating retinal degenerative diseases including CHM.
Date: Tuesday, July 9, 2024
Time: 2 PM - 3 PM ET
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